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Chembiotek is a high-end integrated contract research services organisation, complementing R&D efforts of its pharmaceutical and biotechnology research partners. |
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The research expertise encompasses:
• Combinatorial chemistry
With the infrastructure and the scientific skills to create focused compound libraries for its collaborators and partners, Chembiotek uses widely accepted techniques for parallel synthesis of multiple compounds directed at drug targets. |
• Medicinal chemistry
Working with its collaborators in their core medicinal chemistry area by participating in lead generation, lead optimization and structure activity relationship studies. |
• Custom synthesis
Asymmetric synthesis of novel molecules with highest degree of multi-center chirality. |
• Process Chemistry
Development of process related parameters such as route scouting, process optimization, product isolation, product purification and scale up. Facilities including well-established kilo laboratory for the synthesis of compounds in multi grams to kilograms level. |
• Biological research capabilities
Core service capabilities include assay development and screening in anti-cancer, anti-inflammation, diabetes, CNS, Signal transduction pathways, free radical and receptor binding; homology modeling and drug design. |
• Computational Biology and Bio physics
The computation group has developed proprietary algorithms to address a variety of pharmaceutical challenges. Programs have been developed for virtual library generation, screening of libraries for lead-like properties and for the docking of small molecules with biological macromolecules. In-house computational tools for predicting ADME related properties of compounds in a high throughput fashion have also been developed. |
To keep pace with the changing dynamics of the industry, expanding client base and a compelling need to enhance the existing scientific strength, Chembiotek commenced operations from its second state-of-the-art facility at the International Biotech Park at Pune (India). The clientele of Chembiotek includes leading international pharma and biotech companies from Europe and the USA.
For more details visit: www.chembiotek.com
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