Safety & Toxicology
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Safety & Toxicology

Cardiovascular Safety

  • hERG
    • Radio-Ligand Binding
    • Fluorescence Polarization
    • Manual Patch Clamp
  • NaV1.5

Genetic Toxicology

  • AMES Test
    • Plate Incorporation
    • AMES-MPF (Xenometric)
  • Micronucleus (IVMN)
    • In Vitro:
      • CHO-K1
      • Human peripheral blood
    • In Vivo:
      • Mice blood
      • Mice bone marrow
  • Chromosomal Aberration (CA) – CHO-K1
  • UmuC

In Vitro Toxicology

  • Phospholipidosis – CHO-K1/HepG2 cells, NBD-PE uptake, Fluro/colorimetry
  • Hemolysis – Human/Rat/Mice Blood, hemoglobin in plasma by colorimetry
  • Cell viability/proliferation assay – MTT, Cell Titre(ATP) Glo, LDH release
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