A Simple, Convenient, Highly Regioselective Synthesis of Isobenzofuran-1(3H)-ones (phthalides) as well as Maculalactone A & B, the Bioactive Butyrolactones

Published in: Journal, Volume : 13, Issue : 2, Pages : 127-134

DOI : 10.2174/1570178613666151124200300

Author : Joardar, Soumen; Chakravorty, Santanu; Das, Sakti P.

Abstract : Simple, convenient, one step protocol for the synthesis of isobenzofuran-1(3H)-ones (phthalides) from phthalate esters in moderate to good yields were developed. Short and effective route to prepare two bioactive butyrolactones, viz., maculalactone A and B were also demonstrated.