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Medicinal Chemistry Synthesis Chemistry

TCGLS offers integrated Medicinal Chemistry services to clients across multiple therapeutic areas encompassing oncology, CNS, pain and inflammation, metabolic disorders, and infectious diseases.

Salient Features

  • Experienced project leaders with a strong track record of success from target proposal to delivery of PCC through creation of IP
  • Proven ability to advance challenging discovery programs and emulate project goals/timelines through valuable decision making in medicinal chemistry
  • Experienced program management/leadership team
  • Competitive landscape search and generation of top-line SAR and thorough analysis of the series known in the public domain
  • Design of new chemotypes having preferred physicochemical properties using scaffold – hopping approach and/or structure-guided drug design
  • Synthesis of molecules done in singleton or library mode, thereby focusing on productivity and cycle time management, with real-time problem solving with the help of our state-of-the-art infrastructure, compound management facility, and scientific databases, with the support of a very smooth and streamlined procurement and outbound logistics department
  • Track record of innovation demonstrated with the co-authorship of 82 patents and publications, and the identification of 5 development candidates.